As I see you already saw old threads ...there was few reasons this happened to me...and you can use Mozila or Chrome developer tools ...in mozila go to inspector than switch to network tab and find POST request for module/service/options(or something like that...will se it broken..completed request will be green)and check response...on servers I had this issue...in most case it was error "oh no mysql has gone...." And this was resolved with increased mysql_wait_timeout and/or mysql_allowed_package